Biologique Recherche Sérum PIGM 400
Biologique Recherche Sérum PIGM 400
Brightening, Anti-Dark Spot Serum
Biologique Recherche Sérum PIGM 400
Biologique Recherche Sérum PIGM 400
Brightening, Anti-Dark Spot Serum
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Sérum PIGM 400 is specially formulated to prevent dark spots from appearing, reduce the appearance of existing pigmentation marks, and brighten and even out the complexion.
Key Features
- Visibly fades dark spots and discoloration
- Prevents new pigmentation from forming
- Brightens and evens out dull, uneven skin tone
- Antioxidant protection against free radical damage
- Lightweight and fast-absorbing formula
Suited to
Ideal for all skin types struggling with:
- Dark spots or sun spots
- Uneven skin tone
- Dull, discolored, or lackluster skin
- Post-acne pigmentation
- Free radical damage
How to Use
Apply Sérum PIGM 400 before Crème PIGM 400, in the morning and/or evening on the entire face to illuminate the complexion and/or topically on the dark spots (face, forearms, cleavage and hands).
Key Ingredients
Watercress Sprout Extract and Soy-based Pure Genistin: This extract regulates the formation of melanin and lipofuscin and reduces their accumulation in the skin by activating proteasome. It reduces the pigmentation of brown spots in a targeted way(in vivo), prevents photo-induced aging and evens out skin pigmentation(in vivo).
Plum Pulp Extract: Plum pulp is known for its lightening properties (in vivo): it limits melanogenesis by inhibiting melanin phagocytosis by keratinocytes (in vitro). It also improves the skin’s barrier effect, increases hydration (reducing Trans Epidermal Water Loss –in vivo) and improves the skin’s structure (in vivo).
Sea Lily Extract: Sea Lily Extract is a lightening agent (in vivo): it inhibits melanogenesis by reducing the dendricity of the melanocytes (in vitro) and by inhibiting the synthesis of Substance P receptors on the surface of the dendrites (in vitro). It also inhibits the expression of POMC (protein precursor of α-MSH) and the synthesis of intracellular melanin. As a result, there is a reduction in the size of dendrites, the size of pigmented spots, and in the coloration of spots.
Sea Fern(Seaweed) Extract: This is a lightening agent (in vivo) that also helps reduce the size of pigmented spots (in vivo): It controls the number, size and maturation of melanosomes (in vitro), inhibits the activation of melanogenesis by endothelin (in vitro) and the activation of tyrosinase by gene MITF (in vitro), as well as the expression of genes involved in the migration, production and exportation of melanin (in vitro).
Wasabi Extract: Wasabi is a Japanese plant (of the Brassica family) that only grows in rivers with very pure water. Wasabi is known for its antiseptic properties (in vitro) thanks to the three families of molecules making it up (oxidoreductases, isocyanates, glucosinolates).It traps and neutralizes certain free radicals (in vitro).
Ingredients
WATER (AQUA), COCO-CAPRYLATE/CAPRATE, GLYCERIN, BUTYLENE GLYCOL, PENTYLENE GLYCOL, LACTOBACILLUS/WASABIA JAPONICA ROOT FERMENT EXTRACT, SODIUM ACRYLATES COPOLYMER, HYDROLYZED WHEAT FLOUR, HYDROLYZED PRUNUS DOMESTICA, HELIANTHUS ANNUUS (SUNFLOWER) SEED OIL, PALMARIA PALMATA EXTRACT, CYSTOSEIRA TAMARISCIFOLIA EXTRACT, SOY ISOFLAVONES, LEPIDIUM SATIVUM SPROUT EXTRACT, PANCRATIUM MARITIMUM EXTRACT, CITRIC ACID, DIMETHYLMETHOXY CHROMANOL, PROLINE, TOCOPHEROL, LECITHIN, MALTODEXTRIN, POLYGLYCERYL-6 CAPRYLATE, TRIETHANOLAMINE, ALCOHOL, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, PHENYLPROPANOL.
Shipping & Returns
For international orders, please note that duties and taxes may apply. These are calculated by the individual carriers at the time of delivery and are the responsibility of the customer.

Complementary Treatments
Enhance this ritual with an in-studio treatment designed to support skin health from within.
This formula is often used within our facials as the first cleanse. It dissolves impurities, makeup, and excess oil, preparing the skin for what follows while preserving barrier integrity.
For new clients, we recommend a Discovery Consultation, so that your treatment plan is curated to your specific needs and goals.